Play this card right after the attacker plays a card and pays their energy costs. The defender does 4 stages of power drain on the attacker, no matter what he is doing to the defender.
You'd have to last against him alone for five minutes. It's up to you.
Errata:
Treat this card as if it read, “Use when needed, immediately after your opponent attacks you (this can be a physical or energy attack) and pays any costs for that attack. Lower your opponent’s Main Personality 4 power stages immediately when played.”